1 st generation of products used for 1 st indications of endopeel technics ( like the 1/3 superior of the face) led to some necrosis because of the presence of phenol in the composition.
Unfortunately some colleagues who wish to buy products at low cost , are taking big risks using any product containing phenol in the composition.Cases of necrosis have been reported with phenol. 

Fortunately we are now at the 6 th generation of endopeel`s products and techniques, really safe and the official products never gave any complications at the differences of dangerous copies using phenol.


 Einstein used to say that it was easier to break an atome than to break prejudges.

 We do not have the right to open our mouth if our mind is close.

 Courteline : Passer pour un idiot aux yeux d un imbécile est un plaisir de fin gourmet.
                 Look like an idiot in the eyes of a fool is a fun foodie


Here HA represents the molecular form of the weak acid with where H is the atom of hydrogen
A- represents the anion and H+ the proton, which in solution leads to the ion hydronium H30+     Ka is the constant of acidity . The pKa of endopeel carbolic acid is 6.65


Carbolic Acid and Phenol have been considered similar for most organic chemistry engineers as medical doctors, pharmacists ...

In fact carbolic acid is a weak acid and phenol is a strong basis.

That means that carbolic acid and phenol like on the image are same in organic chemistry formula development, but they are completely different concerning endopeel in general chemistry and physico chemistry.

There are 3 main differences :

1-Resonance stabilization of the phenoxide anion by the aromatic ring.In this way, the negative charge on oxygen is shared by the ortho and para carbon atoms. That is why carbolic acid is used instead of phenol for endopeel techniques ( which lead to medical liftings obtained by chemical myoplasty, myopexy and myotension)

2-Increased acidity in the result of orbital overlap between the oxygen`s lone pairs and the aromatic system.

3-The dominant effect is the induction from the sp2 hybridized carbons;the comparatively more powerful inductive withdrawal of electron density that is provided by the sp2 system compared to an sp3 system allows the great stabilization of the oxyanion

 Bibliographic Reference 


1-Dewandre L., Tenenbaum A.. Chemical Peels of Drs. Mark G. Rubin and Rebecca Tung 2 nd Edition. Imprint: Saunders. Chapter 1: Chemistry of Peelings and Hypothesis of the Mechanism of Action ISBN: 978-1-4377-1924-6. Copyright: 2011



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